Evidence-Based Information and Analysis
How a simple framework reveals that “proven” therapies often lack value while the “unproven” ones lack only approval A Midwestern Doctor May 23, 2026 Story at a Glance: As decisions always have pros and cons, making the correct one is often quite challenging. One framework, “expected value” (EV), solves this puzzle by calculating the relative … Read more
The extensive evidence behind DMSO’s ability to regenerate spinal cord injuries, treat “incurable” back pain, and transform spinal medicine — and how to use it A Midwestern Doctor May 16, 2026 ∙ Paid Story at a Glance: DMSO is an “umbrella remedy” whose combination of therapeutic properties (improving circulation, reducing inflammation, protecting cells, and reviving dying … Read more
The Forgotten Side of Medicine DMSO is a Miraculous Therapy for Chronic Pain and Musculoskeletal Injuries The decades of evidence DMSO revolutionizes the practice of medicine A Midwestern Doctor Sep 29, 2024 ∙ Paid Story at a Glance •The standard approach for treating pain and musculoskeletal injuries typically involves giving NSAIDs (e.g., ibuprofen), and in … Read more
The Forgotten Side of Medicine How DMSO Heals Nerves and Eliminates Neuropathic Pain Why a single agent, through its forgotten biophysical effects, can reverse an improbable range of “incurable” neurological conditions. A Midwestern Doctor Jun 14, 2026 Story at a Glance DMSO is an “umbrella remedy” whose combination of therapeutic properties (improving circulation, reducing inflammation, … Read more
Pernicious anemia has documented familial prevalence. First-degree relatives of PA patients carry a risk four times higher than the general population, and among siblings the figure is higher still — roughly six times the baseline rate. This reflects shared genetic architecture that shapes immune function across generations. B12 deficiency more broadly also clusters in families … Read more
Autoimmune diseases often cluster within the same individual and family. This article examines helminthic therapy through the lens of immune training, microbiome ecology, and transgenerational biology, exploring evidence that the absence of co-evolved organisms may contribute to immune dysregulation across diseases and generations. It reviews current research on regulatory T cells, the microbiome-immune axis, maternal transmission, and the broader implications of biome depletion for understanding autoimmune disease.
Vagal Tone Deficit — Mechanistic Reference Laurel Fitzhugh — March 2026 | Updated: 9/16/2026 Systemic and Mechanistic Relationships — Personal Reference I. The Foundational Deficit: Vagal Tone A. Developmental impairment Continuous secondhand smoke exposure from prenatal period through age 17; direct tobacco use age 17 to present Prenatal and early childhood smoke exposure has documented … Read more
Neurological Pattern Reference Personal Reference — Laurel Fitzhugh Initial capture: May 2026 | Updated: September 16, 2026 Status: Draft — working document, requires updating as new information develops I. The Central Question A primary neurological or systemic vascular condition may have been present since early adulthood or before, expressing itself across multiple systems simultaneously. The … Read more
SetPoint VNS — Responder Analysis Laurel Fitzhugh — May 2026 | Updated: September 16, 2026 Status: Second draft, working document Status Device implanted September 1, 2026, at Mayo Clinic Arizona by Dr. Jonathon Parker. Not yet activated. Activation scheduled September 23, 2026 at Arizona Arthritis & Rheumatology, consistent with the standard division of labor for … Read more
III — The Gut Cluster Laurel Fitzhugh — September 16, 2026 | Status: Overview, substantially revised This document orients the references that make up the gut cluster. Each addresses a different layer of the same system; together they form the case for how gut-barrier dysfunction drives systemic inflammatory amplification throughout this clinical picture. This overview … Read more
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